They are Jigawa Golden Stars, FC Ifeanyi Ubah, Warri Wolves and Adamawa United.
The four teams will now drop down to the Nigeria National League (NNL).
Ifeanyi Ubah, Wolves and Adamawa were all relegated before the last day of the season.
They were joined by Jigawa Golden Stars, who lost 2-0 at MFM FC on the last day of the campaign.
Wikki, Heartland and Abia Warriors all escaped the drop.
Akwa United were crowned NPFL champions for the first time this year.
NPFL: Four clubs to be relegated to NNL confirmed
Copyright © 2019 - 2021 | TryNaija